Gene Regulatory Network of TF family CREB/CREM in human
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
8→CREB1: DHX9, TORC2, MECT1, GLRX, APEX1, MECP2, NXN, TXN.
CREB1→180: CEBPB, EGR1, FLI1, SMAD6, ATF3, PPARA, PPARG, RARB, BCL2, BRCA1, STAT3, CDK5, SPRY2, CFTR, CGA, CHGA, CDC37, MYST2, CHRNA7, CPT1A, CR2, CRHR1, ADRA1A, CTF1, ADRB2, ADRB3, CYP11A1, CYP11B1, CYP11B2, CYP19A1, CYP27B1, DAF, DBH, DDX5, DIO2, DLD, DRD1, DSIPI, ELN, ERBB2, ERF, PPRC1, FLT1, FN1, NR5A1, B3GAT3, GDNF, GGT1, RNU4C, GH1, GNRH1, GNRHR, NR3C1, GRM5, GSTP1, HFE, HLA-DOB, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-G, HMOX1, HPGD, HTR2A, ID2, IFNG, IFNGR1, IGFBP1, CYR61, FAS, IL1B, IL6, IL10, AQP2, AQP3, INHBA, INS, AREG, KCNN3, ARG1, LDHA, LTC4S, LYN, MCAM, ME2, ARVD1, MHC2TA, MITF, ACHE, NR3C2, MOG, MSMB, MUC1, MUC4, MUC5B, MYH10, ATP1A1, NF1, NFE2, NOS1, NPC1, NRAS, NTS, NR4A2, OAT, ODC1, PCSK6, RRM2B, SERPINB2, PDCL, PCK2, PCSK1, PDE4D, PDE7A, PDYN, PMP22, TLR9, POLB, POLD2, POLR2A, AVPR1B, PSEN1, RETN, PTH, PTGS1, PTGS2, BCKDHA, REN, REV3L, RN7SL1, RPL10, RPS3A, BDKRB1, BDNF, CCL5, SFTPA2, SLC5A5, SLC6A4, SLC9A1, SLC19A1, SLC20A1, SOD2, SPRR1A, SRM, BST1, TAT, TRA@, TRB@, TRD@, TF, TFRC, TG, TGFB1, TGFB2, TGFB3, TIMP1, TNF, TOP1, TPH1, TPO, TRH, UBE2I, UCP1, UGT8, VGF, VIP, CXCR4, CALCA, NR4A3, RUNX1, CCK, SIAT9, EXO1, CD4, CD8A, FTMT, TNFRSF8, SPATA2, CDC2L2.
CREM→5: ACE, GPX4, LDHC, ACR, PLN.
CREB1 + CREM→14: ETV3, FOS, JUN, ICAM1, IL2, IL5RA, LOR, PCK1, PLAT, CCND1, TBP, TH, CCNA2, CCNA1.
Gene Regulatory Network of TF family CREB/CREM in mouse
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Creb1→93: Bcl2, Brca1, Cebpd, Fos, Junb, Ppara, Stat3, Rarb, Maml1, Tcrd-V, Cdc2b, Dut, Slc5a5, Adcy8, Barx2, Bdkrb1, Cacna1s, Ccnd1, Ccnd2, Cd3d, Cdc2a, Cdv1, Chga, Chgb, Crebbp, Crh, Cryaa, Ctf1, Cyp11a1, Fst, Galr1, Gfap, Gnrhr, Grin2b, Hspa5, Gzmb, H2-Aa, Hfe, Hgf, Hmox1, Nr4a1, Hpgd, Slc6a4, Elavl1, Ifng, Il2, Il6, Inha, Kcnc1, Anxa1, Ltf, Mif, Mt3, Muc3, Myod1, Nf1, Npr1, Ntsr2, Nr4a2, Pck1, Pcna, Pdha2, Penk1, Per1, Per2, Plat, Plau, Ptger2, Ptgs2, Dusp1, Rdh6, Scg2, Sfrp4, Sftpb, Slc1a3, Slc20a1, Tcra, Tgfb2, Tgm1, Thbs1, Tnfrsf8, Trf, Wisp1, Yy1, Gyg1, Clic4, A130040M12Rik, Slc29a1, Osgep, Nrn1, Myh10, Nfkbiz, H2-D.
Crem→5: Igk, Prm2, Tesk1, Fhl5, Gtf2a1lf.
Gene Regulatory Network of TF family CREB/CREM in rat
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Creb1→63: Bcl2, Brca1, Fos, Jun, LOC367100, Slc5a5, Timp1, Adra1b, Atp1a1, Avp, Bdnf, Comt, Cst4, Grin1, Il6, Inha, Ins1, Ldha, Nppa, Odc1, Pah, Pck1, Penk1, Prl, Scg2, Shbg, Sod2, Sst, Tac1, Tat, Ucp1, Gcg, Andpro, Sds, Aanat, Ccnd3, Bdkrb2, Bglap2, Aldh3a1, Cyp1b1, Slc18a2, Trh, Hspa5, Prkaca, Fn1, Hmgcr, Plat, Cpt1a, Per1, Pdyn, Hfe, Adra1a, Vgf, CysS, RGD:3267, Sstr2, Ccnd1, Crhr1, Thop1, Alas1, Mapk14, Cyp2c23, Sfrp1.
Crem→6: Acr, Ace, Gpd2, Kcna5, Gpx4, Pln.