Gene Regulatory Network of TF family ER in human
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
12→ESR1: FOXO3A, COBRA1, HDAC1, LEP, MAPK1, MAP2K7, NCOA5, SRY, TDG, THRA, SUMO1, XBP1.
ESR1→75: E2F1, ERG, FOXO1A, HOXA10, JUNB, SMAD4, MYB, MYC, SP1, SP3, BRCA1, TFAP2C, CDKN1A, CGA, GADD45G, CYP1A1, CYP1B1, CYP19A1, GADD45A, DSIPI, AKT1, AKT2, ESRRA, F12, FBLN1, GNRH1, LRP16, APOA1, APOE, CYR61, IL8, ITGA2, ITGB1, KRT19, LTF, MDM2, MEP1B, NR3C2, GADD45B, NOS2A, NT5E, TNFRSF11B, SERPINB5, SERPINB9, PIK3CA, PIK3R1, AVP, AVPR1B, MMP26, ZNF398, PTMA, PTPRG, CCND1, REN, CXCL12, SHC1, BMP6, SRC, TAC3, TF, TGFA, TIMP4, UBE3A, WNT7A, CAD, CAV2, RUNX2, SOCS2, WISP2, PCAF, SOCS3, COX7A2L, SLC9A3R1, NCOR1, CDH1.
ESR2→5: CREBBP, MKNK2, MAD2L1, PTPRC, CD68.
ESR1 + ESR2→28: FOS, JUN, PGR, POU1F1, PPARG, RARA, STAT5A, PNRC1, CRHBP, CRYZ, CTSD, NQO1, EGFR, GRIN2D, MAOB, NOS3, OXT, SERPINE1, XPMC2H, SELE, SMARCA1, SMARCA2, TERT, TFF1, C3, VDR, VEGF, EBAG9.
Gene Regulatory Network of TF family ER in mouse
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
5→Esr1: Ncoa1, Btg1, Btg2, Cdc25b, Cited1.
Esr1→22: Notch1, Pgr, Apoe, S100g, Csk, Gnrh2, Grin2d, H19, Hgf, Isl1, Jag1, Ltf, Mdm2, Nos2, Tnfrsf11b, Oprm1, Prkca, Prl, Rdh6, Tnfsf11, Nr0b2, Gcs1.
Gene Regulatory Network of TF family ER in rat
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Esr1→18: Cebpa, Jun, Sp1, Stat5a, Tff1, Nr0b2, Pik3ca, Akt1, Bdnf, Calb3, Penk1, Ptgs1, Lhb, Cyp1b1, Star, Igfbp6, Cyp11a1, Galr1.
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