Gene Regulatory Network of TF family PPAR in human
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
5→PPARG: E2F1, TP53, CSF1, SIRT1, RORA.
PPARA→21: CITED2, DHRS4, CPT1A, CYP1A1, FABP1, FABP3, ACSL1, FGB, NOX1, GOT1, HMGCS1, HMGCS2, APOC3, LIPE, COX1, NFKBIA, APOB48R, SLC10A2, UGT2B4, ACOX2, FADS2.
PPARG→36: ESR1, ESR2, SMAD3, POU2F1, RARB, BCL2, NR1H3, CDKN1A, ADAM28, PPARGC1A, GDEP, CYP19A1, CYP27A1, DBI, EGFR, NCOA6, GCK, ACAA1, HES1, APOE, IL6, ATP2A2, TNFRSF11B, UGT1A9, PPP2R2C, BAAT, PTGER2, PTHLH, SAT, SUMO1, NCOA4, CASP3, CD83, ACDC, ADAMTS4, TNFRSF5.
PPARA + PPARG→14: GATA3, EDN1, AKT1, APOB, MMP9, ACOX1, PCK1, ADIPOR1, RETN, PTGS2, UCP1, ADIPOR2, CD36, NR1D1.
PPARA + PPARD + PPARG→16: MYB, MYC, SEMA6B, GADD45G, CYP4A11, GADD45A, FCER1A, APOA1, LIPA, LPL, GADD45B, SERPINE1, ANGPTL4, PDHA1, VEGF, CCND2.
Gene Regulatory Network of TF family PPAR in mouse
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Ppara→20: Cebpb, Hdl1, Hdl2, Hdl3, Hdl4, Aip, Abcc2, Cyp7a1, Hsd11b1, Hspcb, Cited2, Mttp, Nfkbia, Nox1, Apob, Nrbf1, BC013476, Dhrs4, Hdl5, Acox2.
Ppard→5: Ncoa3, Ncoa2, Ncor1, Ncor2, Nrip1.
Pparg→34: Bcl2, Egr1, Rarb, Plin, Abcg1, Acaa1, Fabp4, Apoe, Atp2a2, Cap1, Casp3, Dbi, Fabp2, Fn1, Hgf, Fabp5, Nos2, Pex11a, Ppargc1a, Scand1, Ptger2, Ptgs2, Sat1, Hmgcs1, Sumo1, Ucp1, Ucp2, Nr1h3, 8430420C20Rik, Ugt1a9, S3-12, Bcmo1, Mpra, C1qtnf3.
Ppara + Pparg→8: Gata3, Nfkb1, Acox1, Aqp7, Acsl1, Slc22a1, Scarb1, Slc27a1.
Ppara + Ppard + Pparg→9: Cd36, Lpl, Mmp3, Pltp, Pparbp, Scd1, Ucp3, Pdk4, Angptl4.
Gene Regulatory Network of TF family PPAR in rat
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Ppara→30: Madh4, Acacb, Cyp4a22, Ehhadh, Mte1, Acadm, Got1, Gstp1, Hmgcs2, Hspa1a, Lpl, Myl2, Retn, Rbp2, Thrb, Dbi, Hsd11b1, Acsl1, Acox2, Ephx1, Cyp1b1, Ahr, Cd36, Hspa1b, LOC367187, Acaca, Thra, Crot, Mlycd, Pdk4.
Pparg→9: Agtr1a, Cat, Gck, Pck1, Nr1d1, Slc2a2, Aldh3a1, Atp2a2, Ucp2.
Ppara + Pparg→5: Mapk1, Cyp4a11, Ucp1, Cyp19a1, Hsd17b4.
Ppara + Pparg + Ppard→8: Hadha, Ren1, Rxra, Ucp3, Rxrb, Acox1, Mthfd1, Rxrg.