Gene Regulatory Network of TF family STAT in human
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
7→STAT3: CNTF, IL18, LEP, MAP3K1, IL20, IL22, SRC.
STAT1→19: GATA3, TP53, CCR5, CSF1, CYBB, FCGR3A, CLC, GBP1, HSPB1, ICAM1, LTC4S, MAT2A, MHC2TA, PLAU, PSMB9, PTGFR, REV3L, TAP1, CASP4.
STAT3→18: CEBPB, CEBPD, MIA2, CRP, STRA13, HGF, HMOX1, BIRC5, HSPCB, FAS, LBP, MCL1, MUC4, OXTR, SERPINA1, RORA, TRH, VEGF.
STAT6→11: ADAM8, ADRA2B, ALOX15, IL1R1, IL4R, IRF4, OPRM1, PRKCA, CCL11, SELE, NCOA3.
STAT1 + STAT3→14: FOS, JUN, CYP19A1, A2M, B3GAT3, HSPCA, NOS2A, REG1A, CCL2, TIMP1, TLR2, VIP, SOCS3, TNFRSF8.
STAT5A + STAT5B→6: ESR1, ESR2, PAX5, CEL, CISH, TRG@.
Gene Regulatory Network of TF family STAT in mouse
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Stat1→11: Bcl6, Pparg, C2ta, Casp4, Tnfrsf6, Gbp1, Cxcl9, Nos2, Shh, Titf1, Scgb1a1.
Stat3→11: Cebpb, Cebpd, Crp, Hspcb, Mcl1, Apcs, Sfrp4, Trh, Vegfa, Vegfb, Vegfc.
Stat6→7: Ncoa3, Adam8, Bcl2l1, Igh-4, Il1r1, Il4, Itgb3.
Stat5a + Stat5b→6: Pax5, Tcrg, Cel, Serpina3g, Serpina3n, Tlr2.
Gene Regulatory Network of TF family STAT in rat
Note:
Ellipses are TFs. Boxes are genes.
Hexagons are the clustered genes. The number of the genes is shown inside.
Red lines indicate the protein-DNA binding is known.
Only official gene symbols are used in the network.
Listing of the gene clusters (TFs are underlined):
Stat3→6: Cebpb, Cebpd, Fgg, Pomc2, LOC299277, Socs3.
Stat5b→5: Onecut1, A2m, Adh1, Cyp2b1, Ins1.