modify this entry

---

NUMBER

GD_ME_MT_DE_G_D_N_0074-SKV

DEFINITION

skeletal-muscle alpha-actinin, exon EF1bSKV, chicken

REFERENCE

Parr, T., Waites, G.T., Patel, B., Millake, D.B., and Critchley, D.R., A chick skeletal-muscle alpha-actinin gene gives rise to two alternatively spliced isoforms which differ in the EF-hand Ca(2+)-binding domain. Eur J Biochem, 1992. 210(3): p. 801-9.

EXPRESSION

MT

REGULATORY FEATURES

encodes part of an EF hand that is involved in Ca++ binding

TEMPORAL REGULATION

usage of the exon decreases during development

TECHNIQUE

PCR and sequencing

ACCESSION

X68800 S53136

SOURCE

genomic DNA

5' SCORE

4.51

3' SCORE

-2.13

ACCEPTOR SITE

atgggatgctag

EXON SEQUENCE

1 gatgaatctg acaatctaca ttctgatgaa tttaaagcct gcctcatcag tctaggagag gttggaaatg acctgcag

DONOR SITE

gtagag

5' EXON

0 catatccgtg ttggatggga gctcctactt actaccattg ctcgaactat caatgaggtt gagactcaga tcctcacaag agatgccaag ggtatcaccc aggagcaaat gaatgacttc agagcatcat tcaatcattt tgacagg

3' EXON

1 ggtgaagctg agtttgctag aatcatgtcc ttggttgacc ccaatggaca aggaaccgtc actttccagt ccttcattga cttcatgacc agagaaacag cagatacgga cacggctgag caagtgatag cttccttcag aatcctggct tcagataag

DISEASE

COMMENTS

mutually exclusive to 0074-sk , non-muscle (variant exon), 3' exon exon EF2 has unusual aag 3' splice site

REVISION

This comment is added on 970314