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NUMBER

RN_UU_BR_00_C_U_U_0131

DEFINITION

metabolic glutamate receptor 1c (mGlu1c)

REFERENCE

Pin, J.P., Waeber, C., Prezeau, L., Bockaert, J., and Heinemann, S.F., Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc Natl Acad Sci U S A, 1992. 89 : p. 10331-5.

EXPRESSION

expressed in different areas of the brain, less abundant than other splice variants, contains stop codon and poly A site

REGULATORY FEATURES

changes the characteristics of the response of the receptor after glutamate stimulation

TEMPORAL REGULATION

na

TECHNIQUE

PCR

ACCESSION

na

SOURCE

cDNA

5' SCORE

NA

3' SCORE

NA

ACCEPTOR SITE

na

EXON SEQUENCE

2 ttttgcttta gaccgccaaa acacttgtct attgaagtga aatgcacctg agatgcagac caaaaataaa aacatcggct ggagagatgg ctcagcggtt aagagcaccc gactgctctt ccagaggtca tgagttcaat tcccagcaac acatggtggc tcacaaccat ctgtaaagag atccgatgaa atcttctggt gtatctgaag acagctacag tgtacttata tataataaat aaataaatct aaaaaaataa aaaata

DONOR SITE

na

5' EXON

1 gggtgcatgt ttactccgaa gatgtacatc atcattgcca aacctgagag gaacgtccgc agtgccttca cgacctctga tgttgtccgc atgcacgtcg gtgatggcaa actgccgtgc cgctccaaca ccttcctcaa cattttccgg agaaagaagc ccggggcagg gaatgccaa

3' EXON

na

DISEASE

COMMENTS

REVISION

This comment is added on 970314 ;; line 1 modified 970107