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NUMBER
- RN_UU_BR_00_C_U_U_0131
DEFINITION
- metabolic glutamate receptor 1c (mGlu1c)
REFERENCE
- Pin, J.P., Waeber, C., Prezeau, L., Bockaert, J., and Heinemann, S.F., Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc Natl Acad Sci U S A, 1992. 89 : p. 10331-5.
EXPRESSION
- expressed in different areas of the brain, less abundant than other splice variants, contains stop codon and poly A site
REGULATORY FEATURES
- changes the characteristics of the response of the receptor after glutamate stimulation
TEMPORAL REGULATION
- na
TECHNIQUE
- PCR
ACCESSION
- na
SOURCE
- cDNA
5' SCORE
- NA
3' SCORE
- NA
ACCEPTOR SITE
- na
EXON SEQUENCE
- 2 ttttgcttta gaccgccaaa acacttgtct attgaagtga aatgcacctg agatgcagac caaaaataaa aacatcggct ggagagatgg ctcagcggtt aagagcaccc gactgctctt ccagaggtca tgagttcaat tcccagcaac acatggtggc tcacaaccat ctgtaaagag atccgatgaa atcttctggt gtatctgaag acagctacag tgtacttata tataataaat aaataaatct aaaaaaataa aaaata
DONOR SITE
- na
5' EXON
- 1 gggtgcatgt ttactccgaa gatgtacatc atcattgcca aacctgagag gaacgtccgc agtgccttca cgacctctga tgttgtccgc atgcacgtcg gtgatggcaa actgccgtgc cgctccaaca ccttcctcaa cattttccgg agaaagaagc ccggggcagg gaatgccaa
3' EXON
- na
DISEASE
-
COMMENTS
-
REVISION
- This comment is added on 970314 ;; line 1 modified 970107