0358

NUMBER: HS_UU_MT_UU_C_D_U_0358
DEFINITION: tpr, translocated promoter region
REFERENCE: Mitchell, P.J., and Cooper, C.S., Nucleotide sequence analysis of human tpr cDNA clones. Oncogene, 1992. 7: p. 383-8.
EXPRESSION: skipping and inclusion of this exon in most cell lines, in HL60 promyelocytic cell line only inclusion
REGULATORY FEATURES: stop codon
TEMPORAL REGULATION: nd
TECHNIQUE: cloning and PCR
ACCESSION: X63105
SOURCE: cDNA
5' SCORE: NA
3' SCORE: NA
ACCEPTOR SITE: nd
EXON SEQUENCE: 2 cttgtagaat tacttttttc ataccagtta
DONOR SITE: nd
5' EXON: 1 caagttacag atttgcgatc acaaaatacc aaaatttcta cccagctaga ttttgcttct aaacgtta
3' EXON: 2 tgaaatgctg caagataatg ttgaaggata tcgtcgagaa a
DISEASE: gene is implicated in activation of met and raf oncogenes
COMMENTS
REVISION: This comment is added on 970314 ;; gene name was corrected (trp -> tpr) in item 2