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NUMBER

DM_ME_BR_UU_C_U_U_0873-c

DEFINITION

para locus, voltage sensitive sodium channel, exon c

REFERENCE

Loughney, K., Kreber, R., and Ganetzky, B. (1989). Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell, 58(6), 1143-54.

EXPRESSION

predominantly expressed in neurons

REGULATORY FEATURES

exon c provides an additional glycosylation site; exon located in transmembrane domain

TEMPORAL REGULATION

nd

TECHNIQUE

screening, cloning

ACCESSION

M32078 M24285 M32079 M32080

SOURCE

cDNA

5' SCORE

NA

3' SCORE

NA

ACCEPTOR SITE

nd

EXON SEQUENCE

1 ctgcgtgttt tcaagctggc caaatcgtgg ccgacgctga atttgctcat atcgattatg ggccgcactg tcggagccct cggcaatctg accttcgtcc tgtgcattat tatcttcata ttcgcggtca tgggcatgca gctgtttggc aagaactaca cagatcac

DONOR SITE

nd

5' EXON

1 ctatttgttg gcggcgagaa gggcaacgat gacaacaaca aagagaagat gtccattcgg agcgtcgagg tggag

3' EXON

1 ggggccatca tagtgcccgt gtactatggc aatctaggct cccgacactc atcgtatacc tcgcatcagt cccga

DISEASE

nd

COMMENTS

exon c mutual exclusive to exon d; the two mutual exclusive exons only differ in two amino acids

REVISION

This entry is modified on 970316 ;; item 13 differs from the seq in U26716