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NUMBER

HS_CA_MT_DE_G_U_N_0937-2

DEFINITION

pregnancy-specific beta1-glycoprotein, PSbetaG HL, exon IB

REFERENCE

Oikawa, S., Inuzuka, C., Kuroki, M., Matsuoka, Y., Kosaki, G., and Nakazato, H.; A pregnancy-specific beta1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: Structures of protein, mRNA and Gene. Biochemical and Biophysical research communications, 1989, Vol. 163 (2): 1021-1031

EXPRESSION

PSbetaG (SP1) is synthesized by syncitiotrophoblasts of the placenta. In this work, HL-60 cells have been used

REGULATORY FEATURES

encodes a stop codon

TEMPORAL REGULATION

beta1-glycoprotein is pregnancy-specific

TECHNIQUE

northern, sequencing

ACCESSION

M32631, M28235

SOURCE

genomic and cDNA sequences

5' SCORE

-13.22

3' SCORE

10.10

ACCEPTOR SITE

tctttgctccag

EXON SEQUENCE

1 atggcctgga tgcccccacc atttcttcct catacaccta ttaccataca ggggaagtcc ccaatctctc ctgcctcaca gactctcacc cactggcaga gcattcttgg ctgattgatg ggaagttcca gcaatcagca caagtgtgct ttattcccca aatcaccaaa acatagaggg atctatgtct gtttcatcca taactcagcc actgatggaa caaatctcat aatcaagagg atcatagtcc ctg

DONOR SITE

gtaactggatccc

5' EXON

3 tggaaactcc caagccctcc atctccagta gcaacttaaa ccccagggag gccatggagg ctgtgatctt aacctgtgat cctgcggctt cagacacaag ctacctgtgg tggatgaatg gtcagagcct ccctatgact cacaggttgc agctgtccaa aaccaacagg accctcttta tatttggtgt cacaaagtat attgcaggac cctatgaatg tgaaatacgg aacccagtga gtgccagcca cagtgaccca gtcaccctga atctcctcc

3' EXON

na

DISEASE

no disease described

COMMENTS

no mRNA encoding Exon IB has been found yet ;; item 15 is exon IA ;; original content of item.16 was 'M28235'.

REVISION

created on 971128