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NUMBER
- DM_CA_MT_DE_G_D_N_m0523-D
DEFINITION
- tyrosine hydroxylase, exon D
REFERENCE
- Birman, S., Morgan, B., Anzivino, M., and Hirsh, J., A novel and major isoform of tyrosine hydroxylase in Drosophila is generated by alternative RNA processing. J Biol Chem, 1994. 269: p. 26559-67.
EXPRESSION
- major form in larva and adult, skipping of exon characteristic for central nervous system
REGULATORY FEATURES
- nd
TEMPORAL REGULATION
- expression increases in adult
TECHNIQUE
- technique
ACCESSION
- U14395
SOURCE
- genomic DNA
5' SCORE
- 8.22
3' SCORE
- NA
ACCEPTOR SITE
- tcgcttttag
EXON SEQUENCE
- 3 TTGAGGAGGA TGTTGAGTTT GAGAGCGTTG AACAGGAGCA GTCGGAGTCG CAGTCGCAGG AGCCAGAAGG CAACCAACAG CCGACCAAGA ACG
DONOR SITE
- gtgagc
5' EXON
- 1 AATGGCTATC CATCCCGCCG TCGCAGCCTG GTGGATGATG CCCGTTTCGA GACCCTGGTG GTCAAGCAGA CCAAACAAAC CGTCCTCGAG GAGGCCCGCA GCAAGGCAAA TG
3' EXON
- 3 ATTACGGTCT CACCGAGGAC GAGATTTTGT TGGCCAATGC CGCCTCCGAA TCCTCGGATG CCGAGGCTGC CATGCAGAGT GCCGCTTTGG TGGTCCGCCT CAAGGAGGGC ATCTCCTCCT TGGGTCGCAT CCTCAAGGCC ATCGAAACCT TCCACGGCAC CGTCCAGCAT GTGGAGTCCC GTCAGTCGCG CGTGGAGGGC GTGGACCACG ATGTCCTCAT CAAGTTGGAC ATGACCCGTG GCAATCTGCT GCAGCTGATC CGCTCCCTCA GGCAGTCGGG CTCCTTCAGC AGCATGAATC TGATGGCCGA CAATAACTTG AATGTCAAGG CTCCGTGGTT CCCCAAGCAC GCCTCCGAAT TGGATAACTG CAACCATCTG ATGACCAAGT ACGAGCCCGA TTTGGACATG AACCACCCCG GATTCGCCGA CAAGGTATAC CGCCAGCGTC GCAAGGAAAT TGCCGAGATC GCATTCGCCT ACAAGTACGG AGACCCGATC CCATTCATCG ACTACTCCGA TGTGGAGGTC AAGACCTGGC GCTCGGTGTT CAAGACCGTT CAGGATCTGG CTCCCAAGCA CGCCTGTGCC GAGTACCGGG CCGCCTTCCA GAAGCTCCAG GATGAGCAGA TCTTCGTGGA GACCCGTCTG CCCCAGTTGC AGGAGATGTC CGACTTTCTG CGCAAGAACA CCGGATTCTC TCTCCGTCCT GCCGCCGGTC TTTTGACTGC CCGGGACTTC CTTGCCTCCT TGGCCTTCCG CATCTTCCAG AGCACCCAGT ATGTGCGCCA CGTTAACTCA CCATACCACA CCCCCGAGCC
DISEASE
-
COMMENTS
- exon always used together with exon C (M0523-C)
REVISION
- created on 971128