Data Modifying Form for the Entry: 0294
Name of the Submitter:
Species:
abbreviation
Splicing Mechanism:
CA
cassette
ME
mutually exclusive exons
A3
alternative 3' splice site
A5
alternative 5' splice site
AE
alternative 3' exon with polyA
RI
retained intron
UU
other or unknown
Tissue:
abbreviation
Temporal (developmental) Regulation:
DE: yes / NO: no / UU: unknown
Sequence Information:
C: cDNA / G: genomic DNA / U: unknown
Promoter Use:
F: follows / D: different / U: unknown
Disease Involvement:
Y: yes / N: no / U: unknown
4 Digits Internal Number:
Name of the Gene:
vascular cell adhesion molecule-1, exon 5
Give the Full Reference, Including Title:
@92308860 Osborn, L., Vassallo, C., and Benjamin, C.D., Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule-1. J Exp Med, 1992. 176: p. 99-107.
Expression Pattern (e.g., expressed in muscle):
nd
Regulatory Features (e.g., encodes stop codon, phosphorylation):
nd
Temporal Regulation:
nd
Technique Used to Determine the Expression Pattern:
cloning, immunostain
Accession number of the exon:
Genomic or cDNA?:
Give 12 nucleotides of the 3' splice site:
Give the Sequence of the Alternatively-spliced Exon:
Reading Frame:
unknown
1st
2nd
3rd
agaaaccatt tactgttgag atctcccctg gaccccggat tgctgctcag attggagact cagtcatgtt gacatgtagt gtcatgggct gtgaatcccc atctttctcc tggagaaccc agatagacag ccctctgagc gggaaggtga ggagtgaggg gaccaattcc acgctgaccc tgagccctgt gagttttgag aacgaacact cttatctgtg cacagtgact tgtggacata agaaactgga aaagggaatc caggtggagc tctact
Give 6 nucleotides of the 5' splice site:
Give the Sequence (or accession number) of the 5' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
tatcacccaa gaatacagtt atttctgtga atccatccac aaagctgcaa gaaggtggct ctgtgaccat gacctgttcc agcgagggtc taccagctcc agagattttc tggagtaaga aattagataa tgggaatcta cagcaccttt ctggaaatgc aactctcacc ttaattgcta tgaggatgga agattctgga atttatgtgt gtgaaggagt taatttgatt gggaaaaaca gaaaagaggt ggaattaatt gttcaag
Give the Sequence (or accession number) of the 3' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
cattccctag agatccagaa atcgagatga gtggtggcct cgtgaatggg agctctgtca ctgtaagctg caaggttcct agcgtgtacc cccttgaccg gctggagatt gaattactta agggggagac tattctggag aatatagagt ttttggagga tacggatatg aaatctctag agaacaaaag tttggaaatg accttcatcc ctaccattga agatactgga aaagctcttg tttgtcaggc taagttacat attgatgaca tggaattcga acccaaacaa aggcagagta cgcaaacact ttatgtcaat g
Disease or Abnormal Processing Described?:
Comments:
gene structure, chromosomal localisation and sequence reported in: <<@91352090 Cybulsky, M.I., Fries, J.W., Williams, A.J., Sultan, P., Eddy, R., Byers, M., Shows, T., Gimbrone, M.A., and Collins, T., Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene. Proc. Natl. Acad. Sci. U.S.A, 1991. 88: p. 7859-7863.>>
Revision (will be updated automatically!):
This comment is added on 970314
To submit the data, press this button:
To clear the form, press this button:
Go to
Alternative Splicing Database Home Page
nakai@imcb.osaka-u.ac.jp