Data Modifying Form for the Entry: 0937-2
Name of the Submitter:
Species:
abbreviation
Splicing Mechanism:
CA
cassette
ME
mutually exclusive exons
A3
alternative 3' splice site
A5
alternative 5' splice site
AE
alternative 3' exon with polyA
RI
retained intron
UU
other or unknown
Tissue:
abbreviation
Temporal (developmental) Regulation:
DE: yes / NO: no / UU: unknown
Sequence Information:
C: cDNA / G: genomic DNA / U: unknown
Promoter Use:
F: follows / D: different / U: unknown
Disease Involvement:
Y: yes / N: no / U: unknown
4 Digits Internal Number:
Name of the Gene:
pregnancy-specific beta1-glycoprotein, PSbetaG HL, exon IB
Give the Full Reference, Including Title:
@89391954 Oikawa, S., Inuzuka, C., Kuroki, M., Matsuoka, Y., Kosaki, G., and Nakazato, H.; A pregnancy-specific beta1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: Structures of protein, mRNA and Gene. Biochemical and Biophysical research communications, 1989, Vol. 163 (2): 1021-1031
Expression Pattern (e.g., expressed in muscle):
PSbetaG (SP1) is synthesized by syncitiotrophoblasts of the placenta. In this work, HL-60 cells have been used
Regulatory Features (e.g., encodes stop codon, phosphorylation):
encodes a stop codon
Temporal Regulation:
beta1-glycoprotein is pregnancy-specific
Technique Used to Determine the Expression Pattern:
northern, sequencing
Accession number of the exon:
Genomic or cDNA?:
Give 12 nucleotides of the 3' splice site:
Give the Sequence of the Alternatively-spliced Exon:
Reading Frame:
unknown
1st
2nd
3rd
atggcctgga tgcccccacc atttcttcct catacaccta ttaccataca ggggaagtcc ccaatctctc ctgcctcaca gactctcacc cactggcaga gcattcttgg ctgattgatg ggaagttcca gcaatcagca caagtgtgct ttattcccca aatcaccaaa acatagaggg atctatgtct gtttcatcca taactcagcc actgatggaa caaatctcat aatcaagagg atcatagtcc ctg
Give 6 nucleotides of the 5' splice site:
Give the Sequence (or accession number) of the 5' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
tggaaactcc caagccctcc atctccagta gcaacttaaa ccccagggag gccatggagg ctgtgatctt aacctgtgat cctgcggctt cagacacaag ctacctgtgg tggatgaatg gtcagagcct ccctatgact cacaggttgc agctgtccaa aaccaacagg accctcttta tatttggtgt cacaaagtat attgcaggac cctatgaatg tgaaatacgg aacccagtga gtgccagcca cagtgaccca gtcaccctga atctcctcc
Give the Sequence (or accession number) of the 3' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
na
Disease or Abnormal Processing Described?:
no disease described
Comments:
no mRNA encoding Exon IB has been found yet ;; item 15 is exon IA ;; original content of item.16 was 'M28235'.
Revision (will be updated automatically!):
created on 971128
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