Data Modifying Form for the Entry: M0339
Name of the Submitter:
Species:
abbreviation
Splicing Mechanism:
CA
cassette
ME
mutually exclusive exons
A3
alternative 3' splice site
A5
alternative 5' splice site
AE
alternative 3' exon with polyA
RI
retained intron
UU
other or unknown
Tissue:
abbreviation
Temporal (developmental) Regulation:
DE: yes / NO: no / UU: unknown
Sequence Information:
C: cDNA / G: genomic DNA / U: unknown
Promoter Use:
F: follows / D: different / U: unknown
Disease Involvement:
Y: yes / N: no / U: unknown
4 Digits Internal Number:
Name of the Gene:
Gs alpha exon N1
Give the Full Reference, Including Title:
@93252868 Crawford, J.A., Mutchler, K.J., Sullivan, B.E., Lanigan, T.M., Clark, M.S. and Russo, A.F. (1993) Neural expression of a novel alternatively spliced and polyadenylated Gs alpha transcript. J Biol Chem 268(13): 9879-85.
Expression Pattern (e.g., expressed in muscle):
most abundant in brain, intermediate levels in skeletal muscle low levels in all other tissues
Regulatory Features (e.g., encodes stop codon, phosphorylation):
stop codon
Temporal Regulation:
expression of N1 start at day E14, one day later than N1 skipping
Technique Used to Determine the Expression Pattern:
cloning, Northern
Accession number of the exon:
Genomic or cDNA?:
Give 12 nucleotides of the 3' splice site:
Give the Sequence of the Alternatively-spliced Exon:
Reading Frame:
unknown
1st
2nd
3rd
AGTCTATTAC CCCCACTAGa tgatggctac agtcctccat cttcgctatg tcctacccca gttatcccat tttgcatgct ggaattgccc ggtcttagga aactactaat aagaatacta ttctgttgtc tgggtggggg ggagggggga tgggtcccta acctattacc taacctttag gcgttaagta aaaacagaaa gatgggatga agtctttaat tggcaacagt gtagtagaac agcaatcaga aaacgcatcg atatcttgat aatccgctgt accaaaagtt ggcatctgag aagtgtggca agcccctact gagagagcct cctatgtaat gtgtgctgtg ctaagccctt caaccctact aatacctgca cgtttttctt cctatgactc tacaagtaaa aataagtatt aacactcctg ataaataaaa ctctctgcat gtttcagc
Give 6 nucleotides of the 5' splice site:
Give the Sequence (or accession number) of the 5' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
CTGCTGGGTG CTGGAGAGTC TGGCAAAAGC ACCATTGTGA AGCAGATGAG GATCCTACAT GTTAATGGGT TTAACGGAGA GGGCGGCGAA GAGGACCCGC AGGCTGCAAG GAGCAACAGC GATGG
Give the Sequence (or accession number) of the 3' Common Exon:
Reading Frame:
unknown
1st
2nd
3rd
na
Disease or Abnormal Processing Described?:
nd
Comments:
usage of the alternative exon induced by dexamethasone
Revision (will be updated automatically!):
created on Apr 18, 1998
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Alternative Splicing Database Home Page
nakai@imcb.osaka-u.ac.jp