Gibbs program: parameters' description.

GibbsDNA Sites and Motif Sampler is the simple modification of original Gibbs Sampler (see Neuwald AF, et al. and Lawrence CE , et al. ) adjusted for DNA sequence analysis. Several options have been added and the work is still in progress.

Sites sampler

file lengths [options]

Motif sampler

file lengths expect [options] lengths = [,]: lengths of elements for each type
expect = [,]: expected number of elements for each type
[,] = numbers for each element (e.g. "10,12,15" for 3 types)

Options:

-C prob. cutoff (0 < C <= 1) for near optimum sampling [real]

-c number of cycles between shifts (sites sampler)
or maximum number of cycles per run (motif sampler) [int]

-d DON'T use fragmentation (i.e., column sampler)

-f create a scan output file (file.sn)

-I interactively specify #sites/sequence (sites sampler)
(default: one site of each type per sequence)

-L set rapid convergence limit (higher = longer to converge) [int]
-m set maximum number of cycles in each run (sites sampler) [int]

-o use element order in probabilities (sites sampler)
(each sequence must contain the same number of elements)

-p number of pseudo counts for product multinomial model [float]

-q pseudo counts for ordering model (sites sampler) [float]

-R set number of near-optimum readings taken [int]

-r randomly shuffle input sequences

-s give seed for random number generator [int]

-t maximum number of sampling runs [int]

-w output wilcoxon rank test information (motif sampler)

-W set fractional weight (0 to 1.0) on priors (motif sampler) [float]

-b1 include both strands as single sequence

-b2 include both strands as separate sequences




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